Sunday, September 27, 2009

What Should You Ask Your Doctor About Malignant Mesothelioma

As you cope with cancer and cancer treatment, you need to have honest, open discussions with your doctor. You should feel free to ask any question that's on your mind no matter how small it might seem. Here are some questions you might want to ask. Nurses, social workers, and other members of the treatment team may also be able to answer many of your questions.

* What kind of mesothelioma do I have?
* Has my cancer spread beyond the primary site?
* What is the stage (extent) of my cancer, and what does that mean in my case?
* Is my cancer likely to be resectable?
* Are there other tests that need to be done before we can decide on treatment?
* How much experience do you have treating this type of cancer?
* Should I get a second opinion?
* What treatment options do I have?
* What is the goal of treatment?
* What do you recommend and why?
* What risks or side effects are there to the treatments you suggest?
* What should I do to be ready for treatment?
* How long will treatment last? What will it involve? Where will it be done?
* How will treatment affect my daily activities?
* What would we do if the treatment doesn't work or if the cancer recurs?
* What type of follow-up might I need after treatment?

In addition to these sample questions, be sure to write down some of your own. For instance, you might want more information about recovery times. Or you may want to ask about clinical trials for which you may qualify.

Websites Specializing in Mesothelioma Lawyers by State

Ways to Find Mesothelioma Lawyers

There are many different ways to contact legal help for mesothelioma patients. Here are a few suggestions.

  • Phone Book / Yellow Pages - By looking in your local phone book, you will be able to find many law offices within your area that may help with mesothelioma. Key words to look for include law, attorney, lawyer, etc. A call to the office will help you decide if they can help.
  • Online Help
    • www.yellowpages.com - This useful site will help mesothelioma patients find lawyers in their area without every having to leave their computer.
    • www.switchboard.com - Very similar to yellowpages.com, this site will allow people suffering with mesothelioma to find other lawyers listed in their area.
    • www.google.com - Google's search engine is one of the easiest ways to find information quickly about a very specific topic such as finding mesothelioma lawyers

A Guide to Mesothelioma

Mesothelioma is a rare form of cancer almost always associated with a previous history of asbestos exposure. Malignant cells are found in the connective tissues lining the chest (pleural mesothelioma), abdominal cavity (peritoneal mesothelioma), and the heart (pericardial mesothelioma).

Exposure:
Almost all cases of mesothelioma can be traced to asbestos exposure. When asbestos fibers are inhaled, they can become trapped in the lungs and that can lead to scarring. Over time this can lead to mesothelioma with a latency period of 20 - 40 years for the disease to show up. It is important to understand that asbestos fibers are found in air samples around the world and that low level exposure is unlikely to lead to cancer.

International Mesothelioma Program

Mesothelioma:

The mesothelium is the sac that lines and protects vital organs such as the heart, the lungs, and the abdominal cavity (stomach). This disease causes the cells of the lining to become abnormal and malignant. About seven thirds of all mesothelioma cases create in the pleural mesothelium or lung lining. The remaining cases, about seven third, create in the abdomen. Never, mesothelioma occurs in other mesothelial tissue, such as around the heart or in the reproductive organs.

The increased incidence of mesothelioma has been closely linked to the rise of the asbestos industry and the use of asbestos in fireproofing and insulation. Between 50% and 80% of patients diagnosed with MPM are aware of exposure to asbestos at some point in their lives. Men are typically affected more, due to the common presence of asbestos in industrial settings. The increasing incidence suggests either that the benefits of legislation to reduce asbestos exposure in the workplace have not yet taken effect, or that asbestos exposure during the 1960's was more widespread than previously believed. In addition, some researchers have implicated exposure to the SV-40 virus, which is known to have contaminated some polio vaccines, as potentially related to this malignancy, but this has not been proven.

Without treatment, most patients will die from mesothelioma within 4 to 12 months from the time of diagnosis. Patients generally die as a result of respiratory failure or pneumonia. Tiny bowel obstruction, resulting from direct extension of tumor through the diaphragm, develops in about one-third of patients. About 10% die of cardiac complications when the tumor invades the pericardium and heart. Seven subtypes of mesothelioma have been identified according to microscopic appearance; these are epithelial, sarcomatoid, and mixed types. A number of studies have demonstrated that the epithelial variant is associated with the best prognosis. Other favorable prognostic variables include younger age, lovely performance status, early stage disease, and lack of chest pain at diagnosis.

The absence of asbestos exposure in a significant percentage of mesothelioma patients is used by some experts to argue for a genetic predisposition. The fact that only about 5% of South African asbestos mine workers developed mesothelioma suggests that other environmental or genetic factors are involved. Another associated risk factor is radiation. Radiation-induced malignant mesothelioma appears to have the same prognosis as asbestos-related mesothelioma.

Mesothelioma-The facts

Defining Mesothelioma
Mesothelioma (pronounced mez-uh-thee-lee-oh-muh) is a form of cancer affecting the mesothelium, the membrane that lines plus protects various organs of the body. Made up of one cell layers, the mesothelium surrounds organs with an outer membrane plus also with a protective sac. This tissue allows the organs to move, helping them perform their essential functions.

The mesothelium protects several organs including the lungs, stomach plus heart. Tumors can exist in any of these organs plus may be not be cancerous. The information covered in the following text is in reference to tumors that are cancerous. The most common types of mesothelioma come in six different forms - pleural mesothelioma, peritonial mesothelioma plus pericardial mesothelioma.

Pleural mesothelioma is the most common type plus is associated with the lining of the lungs. Peritonial mesothelioma, affecting the lining of the stomach has the second most reported cases. The rarest type of mesothelioma is pericardial mesothelioma which is associated with the tissue surrounding the heart.

Symptoms Of Mesothelioma

The majority of people who are diagnosed with mesothelioma are over 65 years of age. Men are also more likely to get this form of cancer. Symptoms are different for the six main types of mesothelioma. These six types are defined by the location of the mesothelioma within the body.
Below is a brief summary of possible symptoms for each of the six types beginning with the most common type of mesothelioma plus ending with the rarest form of the cancer. The symptoms listed are not intended to be used for diagnosis of mesothelioma. If you have been in contact with asbestos or suspect you may have mesothelioma, you should contact your doctor.

Pleural Mesothelioma (lining of the lungs) Symptoms


Peritoneal Mesothelioma (lining of the stomach) Symptoms

* cough
* shortness of breath
* lower back or side chest pain
* fatigue
* difficulty swallowing
* fever


Pericaridal Mesothelioma (lining of the heart) Symptoms

* vomiting
* weight loss
* abdominal pain
* liquid or a noticeable lump in the abdomen


How Mesothelioma Can Be Detected

* irregular heartbeat
* chest pain
* shortness of breath

Mesothelioma is detected plus diagnosed using various methods. CT scans, chest x-rays, tissue scans, MRI scans plus PET scans can be used to detect mesothelioma. Chest x-rays are typically the least useful in early detection, while CT scans are generally the most popular form of detection.
All of these tests are helpful in giving your doctor a clearer picture of your lungs (or the organ in query.) It can be difficult to identify mesothelioma, so your doctor may order several different kinds of tests before a diagnosis is made.

How Mesothelioma Is Treated
While specific treatments should always be discussed with your doctor, treatment for types of mesothelioma generally follows the same rules for treating other types of cancer. Radiation, chemotherapy plus surgery are all ways in which mesothelioma is treated.

Causes Of Mesothelioma
Though mesothelioma is rare, around 2,000 to 3,000 new cases are reported each year in the United States.
While there's studies looking into other causes of mesothelioma (like infection with simian virus 40), exposure to asbestos is the main factor associated with developing mesothelioma. Currently close to 80% of the reported cases are related to asbestos exposure.

Used as insulation in homes, in manufactured products plus found naturally in rocks plus dust, asbestos becomes risky when the fibers are breathed in or swallowed. The fibers may travel to the lining of the lungs or stomach, resulting in damage to the mesothelium.

Because of where asbestos is found (in building products like roofing plus insulation or in mineral deposits), a quantity of those at the highest risk for exposure are construction workers, factory workers plus miners. Mesothelioma does not create quickly plus the risk of developing it depend on the level of asbestos exposure.

The Asbestos Informer

What is asbestos?

Asbestos is a mineral. It is mined in much the same way that other minerals, such as iron, lead, and copper, are. Asbestos is composed of silicon, oxygen, hydrogen, and various metal cations (positively charged metal ions). There are many varieties of asbestos: the three most common are chrysotile, amosite, and crocidolite. Chrysotile fibers are pliable and cylindrical, and often arranged in bundles. Amosite and crocidolite fibers are like small needles. The first commercial asbestos mine -- a chrysotile mine -- opened in Quebec, Canada, in the 1870's. Crocidolite asbestos was first mined in South Africa during the 1980's. Amosite asbestos also comes from Africa and was first mined in 1916. Unlike most minerals, which turn into dust particles when crushed, asbestos breaks up into fine fibers that are little to be seen by the human eye. Often individual fibers are mixed with a material that binds them together, producing asbestos containing material (ACM).

Why has asbestos been so widely used?

Asbestos appealed to manufacturers and builders for a variety of reasons. It is strong yet flexible, and it won't burn. It conducts electricity poorly, but insulates effectively. It also resists corrosion. Asbestos may have been so widely used because few other accessible substances combine the same qualities.

How many products contain asbestos?

Two study estimated that 3,000 different types of commercial products contained asbestos. The amount of asbestos in each product varied from as little as two percent to as much as 100 percent. Many older plastics, paper products, brake linings, floor tiles and textile products contain asbestos, as do many heavy industrial products such as sealants, cement pipe, cement sheets, and insulation.

How long has asbestos been in use?

Asbestos was first used in the United States in the early 1900's, to insulate steam engines. But until the early 1940's, asbestos was not used extensively. However, after World War II, and for the next thirty years, people who constructed and renovated schools and other public buildings used asbestos and asbestos -containing materials (ACM) extensively. They used ACM primarily to fireproof, insulate, soundproof, and decorate. The Environmental Protection Agency (EPA) estimates that there are asbestos containing materials in most of the nation's approximately 107,000 primary and secondary schools and 733,000 public and commercial buildings.

When asbestos fibers are in the air, people may inhale them. Because asbestos fibers are little and light, they can stay in the air for a long time.

How are people exposed to asbestos?

When is ACM most likely to release asbestos fibers?

People whose work brings them into contact with asbestos -- workers who renovate buildings with asbestos in them, for example -- may inhale fibers that are in the air: this is called occupational exposure. Workers' families may inhale asbestos fibers released by clothes that have been in contact with ACM: this is called paraoccupational exposure. People who live or work near asbestos- related operations may inhale asbestos fibers that have been released into the air by the operations: this is called neighborhood exposure.

Damaged ACM is more likely to release fibers than non-damaged ACM. In a 1984 survey, EPA found that approximately 66 percent of those buildings that contained asbestos contained damaged ACM. If ACM, when dry, can be crumbled by hand pressure -- a condition known as "friable" -- it is more likely to release fibers than if it is "non-friable." Fluffy, spray-applied asbestos fireproofing material is generally considered "friable." Some materials which are considered "non-friable," such as vinyl-asbestos floor tile, can also release fibers when sanded, sawed or otherwise aggressively disturbed. Materials such as asbestos cement pipe can release asbestos fibers if broken or crushed when buildings are demolished, renovated or repaired. ACM which is in a heavy traffic area, and which is therefore often disturbed, is more likely to release fibers than ACM in a relatively undisturbed area.

How can asbestos be identified?

The EPA requires that the asbestos content of suspect materials be determined by collecting bulk samples and analyzing them by polarized light microscopy (PLM). The PLM method determines both the percent and type of asbestos in the bulk material. EPA Regional Offices can provide information about laboratories that check for asbestos.

While it is often possible to "suspect" that a material or product is/or contains asbestos by visual determination, actual determinations can only be made by instrumental analysis. Until a product is tested, it is best to assume that the product contains asbestos, unless the label, or the manufacturer verifies that it does not.

Some people exposed to asbestos create asbestos-related health problems; some do not. Two times inhaled, asbestos fibers can easily penetrate body tissues. They may be deposited and retained in the airways and lung tissue. Because asbestos fibers remain in the body, each exposure increases the likelihood of developing an asbestos-related disease. Asbestos related diseases may not appear until years after exposure. Today they are seeing results of exposure among asbestos workers during World War II. A medical examination which includes a medical history, breathing capacity check and chest x-ray may detect problems early. Scientists have not been able to create a "safe" or threshold level for exposure to airborne asbestos. Ingesting asbestos may be harmful, but the consequences of this type of exposure have not been clearly documented. Nor have the effects of skin exposure to asbestos been documented. People who touch asbestos may receive a rash similar to the rash caused by fiberglass.

Does asbestos exposure cause health problems?

Asbestos is

What illnesses are associated with asbestos exposure?

There is no effective treatment for asbestosis; the disease is usually disabling or fatal. The risk of asbestosis is minimal for those who do not work with asbestos; the disease is never caused by neighborhood or relatives exposure. Those who renovate or destroy buildings that contain asbestos may be at significant risk, depending on the nature of the exposure and precautions taken.

Asbestosis is a serious, chronic, non-cancerous respiratory disease. Inhaled asbestos fibers aggravate lung tissues, which causes them to scar. Symptoms of asbestosis include shortness of breath also a dry crackling sound in the lungs while inhaling. In its advanced stages, the disease may cause cardiac failure.

The U.S. Environmental Protection Agency and the Occupational Safety and Health Administration (OSHA) are responsible for regulating environmental exposure and protecting workers from asbestos exposure. OSHA is responsible for the health and safety of workers who may be exposed to asbestos in the workplace, or in connection with their jobs. EPA is responsible for developing and enforcing regulations necessary to protect the general public from exposure to airborne contaminants that are known to be dangerous to human health.

Who regulates asbestos?

EPA's advice on asbestos is neither to rip it all out in a panic nor to ignore the problem under a false presumption that asbestos is "risk free." , EPA recommends a practical approach that protects public health by emphasizing that asbestos material in buildings should be located, that it should be appropriately managed, and that those workers who may disturb it should be properly trained and protected. That has been, and continues to be, EPA's position. The following summarizes the three major facts that the Agency has presented in congressional testimony:

The EPA's Worker Protection Rule (40 CFR Part 763, Subpart G) extends the OSHA standards to state and local employees who perform asbestos work and who are not covered by the OSHA Asbestos Standards, or by a state OSHA plan. The Rule parallels OSHA requirements and covers medical examinations, air monitoring and reporting, protective equipment, work practices, and record keeping. In addition, many State and local agencies have more stringent standards than those required by the Federal government. People who plan to renovate or remove asbestos from a building of a sure size, or who plan to destroy any building, are required to notify the appropriate federal, state and local agencies, and to follow all federal, state, and local requirements for removal and disposal of regulated asbestos-containing material (RACM).

FACT ONE: Although asbestos is dangerous, human risk of asbestos disease depends on exposure.

FACT TWO: Prevailing asbestos levels in buildings -- the levels school children and you and I face as building occupants -- seem to be low, based on accessible data. Accordingly, the health risk they face as building occupants also appears to be low.

FACT THREE: Removal is often not a school district's or other building owner's best course of action to reduce asbestos exposure. In fact, an improper removal can generate a unsafe situation where none previously existed.

FACT FOUR: EPA only requires asbestos removal in order to prevent significant public exposure to asbestos, such as during building renovation or demolition.

What are EPA's regulations governing asbestos?

FACT FIVE: EPA does recommend in-place management whenever asbestos is discovered. Instead of removal, a conscientious in- place management program will usually control fiber releases, when the materials are not significantly damaged and are not likely to be disturbed.

In 1979, under the Toxic Substances Control Act (TSCA), EPA began an asbestos technical assistance program for building owners, environmental groups, contractors and industry. In May 1982, EPA issued the first regulation intended to control asbestos in schools under the authority of TSCA; this regulation was known as the Asbestos-in-Schools Rule. Beginning in 1985, loans and grants have been given each year to aid Local Education Agencies (LEAs) in conducting asbestos abatement projects under the Asbestos School Hazard Abatement Act (ASHAA).

TSCA

The Asbestos NESHAP is intended to minimize the release of asbestos fibers during activities involving the handling of asbestos. Accordingly, it specifies work practices to be followed during renovations of buildings which contain a sure threshold amount of friable asbestos, and during demolitions of all structures, installations, and facilities (except apartment buildings that have no over one dwelling units). Most often, the Asbestos NESHAP requires action to be taken by the person who owns, leases, operates, controls, or supervises the facility being demolished or renovated (the "owner"), and by the person who owns, leases, operators, controls or supervises the demolition or renovation (the "operator"). The regulations need owners and operators subject to the Asbestos NESHAP to notify delegated State and local agencies and/or their EPA Regional Offices before demolition or renovation activity begins. The regulations restrict the use of spray asbestos, and prohibit the use of wet applied and molded insulation (i.e., pipe lagging). The Asbestos NESHAP also regulates asbestos waste handling and disposal.

What are the basic requirements of the Asbestos NESHAP?

Why was the Asbestos NESHAP recently amended?

The Asbestos NESHAP was amended for several reasons. EPA wanted to clarify existing regulatory policies, and to add regulations which explicitly address monitoring and record keeping at facilities which mill, manufacture, and fabricate asbestos. Also, because of the high risk associated with the transfer and disposal of ACM, EPA also wanted to strengthen the requirements which govern asbestos waste disposal by requiring tracking and record keeping. Furthermore, EPA determined that the Asbestos NESHAP needed to take into account the availability of improved emission controls. EPA also wanted to make the NESHAP consistent with other EPA statutes that regulate asbestos.

What sources are now covered by the asbestos NESHAP?

The following activities and facilities are currently regulated by the Asbestos NESHAP:

* Roadways containing ACM.

* The milling of asbestos.

* The commercial manufacture of products that contain commercial asbestos.

* The demolition of all facilities.

* The spraying of ACM.

* The renovation of facilities that contain friable ACM.

* The use of insulating materials that contain commercial asbestos.

* The processing (fabricating) of any manufactured products that contain asbestos.

* The closure and maintenance of inactive waste disposal sites.

* The disposal of asbestos-containing waste generated during milling, manufacturing, demolition, renovation, spraying, and fabricating operation.

* The operation of and reporting on facilities that convert asbestos containing waste material into non-asbestos material.

* The design and operation of air cleaning devices.

* Active waste disposal sites.

* The reporting of information pertaining to technique control equipment, filter devices, asbestos generating processes, etc.

What were the major changes to the Asbestos NESHAP?

Milling, Manufacturing, and Fabricating Sources

Demolition and Renovation

Businesses which are involved in asbestos milling, manufacturing, and fabricating now must monitor for visible emissions for at least 15 seconds at least two times a day (during daylight hours), and inspect air cleaning devices at least two times a week. The facilities must maintain records of the results, and submit each quarter a copy of the visible emissions monitoring records if visible emissions occurred during the quarter. Facilities that install fabric filters (to control asbestos emissions) after the effective date of the revision must provide for easy inspection of the bags.

Owners and operators must give a 10-day notice for planned renovations and demolitions. They must renotify EPA in advance of the actual start date if the demolition or renovation will start on a date other than the two specified in the original notification.

All facilities which are "demolished" are subject to the Asbestos NESHAP. The definition of demolition was expanded to include the intentional burning of a facility, in addition to the "wrecking or taking out . . . any load-supporting structural member of a facility." Owners and operators of all facilities which are to be demolished, and of facilities that contain a sure amount of asbestos which are to be renovated, must now provide more detailed information in notifications, including the name of the asbestos waste transporter and the name of the waste disposal site where the ACM will be deposited.

Topical Vitamin-C anti-aging

Topical vitamin C or ascorbic acid is a popular vitamin being added to skin care products. Currently there's plenty of advertising claims of topical formulation containing antioxidants that will protect against & reverse aging. However, the truth is that plenty of of the available formulations contain low concentrations of antioxidants that are not well absorbed by the skin. Vitamin C on the other hand, is an antioxidant, which when manufactured in to a stable topical formulation, is proven to be effective in protecting against photoaging of the skin.
Vitamin C


How does topical vitamin C work?

Topical vitamin C has shown to protect the skin from UV damage caused by prolonged sun exposure by reducing the amount of free radical formation and/or sunburn cells. Exposure to UV light has also shown to decrease the naturally occurring vitamin C levels in the skin, thus topical application of vitamin C restores these photoprotectant levels. Other studies also suggest that vitamin C may play a part in the collagen biosynthetic pathway by activating collagen metabolism & dermal synthesis of elastic fibres.
What is topical vitamin C used for?

To understand how topical vitamin C works an understanding of the relationship between free radicals & antioxidants in the body is necessary.
Free radicals are molecules created as a by-product of oxygen metabolism as our bodies generate energy at the cellular level. Basically, the oxygen molecule loses one electron, turning it in to a free radical.
Free radical formation can also be augmented by external factors such as pollutants, sunlight, radiation, emotional stress, smoking, excessive alcohol, infection, & some drugs.
Free radicals float around the body looking for electrons to rebalance themselves. If necessary, free radicals steal electrons from normal healthy cells, this being the cause of various conditions ranging from accelerated ageing to deadly cancers.
Antioxidants protect healthy cells by donating an electron to the free radicals. The body produces antioxidants naturally & they can also get them from the foods they eat & from supplements.

Studies have shown the following benefits of using topical vitamin C preparations.
Improve skin appearance by reducing fine lines & wrinkles.
Wound healing as it aids in stabilising collagen.
Protects against or lessens the severity of sunburns.

Healthy diet in summer

International nutrition experts have some common suggestion on healthy diet in summer:

First, four eggs and four steak a week. Nutritionist experts believe that the total obese intake should be less than 25% in total calorie intake. Saturated obese mainly existes in meat, butter and other animal Food. The experts recommended they can only eat 85 grams steak per week divided to four times. Cholesterol in the food are mainly from the eggs and shrimp, the experts recommended that the daily cholesterol intake limited to less than 300 milligrams.

Third, eating fruits and vegetables every day. Experts recommended that they should eat at least four fruits and 500 grams of vegetables per day, which can help people reduce the risk of cancer. Cellulose helps to reduce the risk of heart disease and cancer, so it needs at least 20-35 grams per day of cellulose and the specific approach is to eat a lot of fruit, vegetables and cereals.

Second, eating fish once a week. Fatty acids in fish oils can reduce heart attack and prevent blood vessel blockage. The vast majority of experts recommend they should eat fish once a week at least.

Fifth, the balance of other nutrients and don't be fat. Fat will cause high blood pressure, diabetes and other illnesses. However, genetic factors make some people always so heavy that striving to accomplish "standard" weight may be futile. Such a person should be have normal diet and regular physical exercise.

Fourth, cooking by iron pan and adding calcium tablet. Lacking of calcium and iron will lead to anemia and most of thr people get iron from the food. But for some people who is require of the higher volume of iron still require to replenish iron. For example, pregnant lactating women.

Mesothelioma-Asbestos and Cancer

Mesothelioma

Mesothelioma is a form of cancer that is caused by previous exposure to asbestos. In this disease, malignant cells create in the mesothelium, a protective lining that covers most of the body's internal organs. Its most common site is the pleura (outer lining of the lungs and chest cavity), but it may also occur in the peritoneum (the lining of the abdominal cavity) or the pericardium (a sac that surrounds the heart).
Signs and symptoms of Mesothelioma
Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of liquid in the pleural space are often symptoms of pleural mesothelioma.
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of liquid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face. These symptoms may be caused by mesothelioma or by other, less serious conditions.
Diagnosis
Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Diagnosis begins with a review of the patient's medical history. A history of exposure to asbestos may increase clinical suspicion for mesothelioma. A physical examination is performed, followed by chest X-ray and often lung function tests. The X-ray may reveal pleural thickening commonly seen after asbestos exposure and increases suspicion of mesothelioma. A CT (or CAT) scan or an MRI is usually performed. If a large amount of liquid is present, abnormal cells may be detected by cytology if this liquid is aspirated with a syringe. For pleural liquid this is completed by a pleural tap or chest drain, in ascites with an paracentesis or ascitic drain and in a pericardial effusion with pericardiocentesis. While absence of malignant cells on cytology does not exclude mesothelioma, it makes it much more unlikely, especially if an alternative diagnosis can be made (e.g. tuberculosis, heart failure).
If cytology is positive or a plaque is regarded as suspicious, a biopsy is needed to confirm a diagnosis of mesothelioma. A doctor removes a sample of tissue for examination under a microscope by a pathologist. A biopsy may be completed in different ways, depending on where the abnormal area is located. If the cancer is in the chest, the doctor may perform a thoracoscopy. In this procedure, the doctor makes a little cut through the chest wall and puts a narrow, lighted tube called a thoracoscope into the chest between three ribs. Thoracoscopy allows the doctor to look inside the chest and receive tissue samples.If the cancer is in the abdomen, the doctor may perform a laparoscopy. To receive tissue for examination, the doctor makes a little opening in the abdomen and inserts a special gizmo into the abdominal cavity. If these procedures do not yield enough tissue, more extensive diagnostic surgery may be necessary.
Asbestos and the law

Worldwide, 60 countries (including those in the European Union) have banned the use of asbestos, in whole or in part. The American Bar Association states that a growing number of claimants do not, and may never, suffer from asbestos illness. Because of the fear of a walking statute of limitations, many people file claims who are not presently ill, but have had X-rays that show changes 'consistent with' asbestos disease. This 'now or never filing' is clogging the courts and delaying seriously ill claimants from having their cases heard. To alleviate this problem, the ABA recommends that a clear standard of impairment be implemented, and the statute of limitations not start ticking until a person actually becomes ill.
According to the Environmental Working Group Action Fund, 10,000 people a year die from asbestos-caused diseases the United States, including four out of every 125 American men who die over the age of 50.The Environmental Protection Agency (EPA) has no general ban on the use of asbestos. However, asbestos was four of the first hazardous air pollutants regulated under Section 112 of the Neat Air Act of 1970, and many applications have been forbidden by the Toxic Substances Control Act (TSCA).
According to a September 2004 of the American Journal of Respiratory and Critical Care Medicine, asbestos is still a hazard for 1.3 million US workers in the construction industry and for workers involved in the maintenance of buildings and equipment.

What is mesothelioma

There's also benign (noncancerous) tumors of the mesothelium, and these are also called mesothelioma.
Symptoms and diagnosis

Malignant mesothelioma is a cancer of the mesothelium. The mesothelium is a layer of tissue that surrounds plenty of of the body's organs. The mesothelium serves as a buffer between a quantity of the body's moving parts (the beating heart) and more rigid parts (breastbone).

Mesothelioma can have vague symptoms shared with plenty of other, less serious conditions, so a doctor will try to rule out those conditions through a physical exam, which could include x-rays and tests of lung function. Imaging tests such as MRIs, CAT scans and PET scans may be completed.

Symptoms differ depending on where the mesothelioma occurs in the body. Pleural (lung) mesothelioma, the most common type of mesothelioma, may cause symptoms such as breathing problems and chest pain.

Pleural mesothelioma is the most common type (75 percent of diagnoses) of malignant mesothelioma. This is a cancer of the mesothelial tissue surrounding the lungs and lining the chest wall.

The only way to definitively diagnose mesothelioma is through analysis of tissue taken from the mesothelium through biopsy. The biopsy can be completed by inserting a camera and surgical instruments through a small incision (thoracoscopy in the chest or laparoscopy in the abdomen) or by opening up the abdominal or chest cavity (thoracotomy or laparotomy). The tissue sample will be examined through a microscope to detect patterns that differentiate it from benign cells or other types of cancerous cells. If diagnosis is still unclear, tests for different chemicals in the cells or genetic testing of the cells may be needed, or an electron microscope can offer a closer look at the cells.
Types of mesothelioma

Pericardial mesothelioma is rare; it affects the mesothelial tissue surrounding the heart.

Peritoneal mesothelioma is the second-most common (10 percent-20 percent). It affects the mesothelial tissue surrounding the abdominal organs.

Mesotheliomas of the tunica vaginalis testis (in men) and tunica serosa uteri (in women) are rare. These cancers affect the mesothelial tissue surrounding the male or female internal reproductive organs.
Stages of disease

Only pleural mesothelioma has a formal staging system. Staging is mainly used to give a prognosis and help select a work of treatment.

Stage I: Localized, has not spread.

The main staging system, used by the American Joint Committee on Cancer, uses a TNM system to choose a stage: T for tumor, (size and extent of spread); N for nodes (extent of spread to lymph nodes); and M for metastasis (extent of spread to far-away organs). Each pleural mesothelioma case will be given a ranking, from low (less severe) to high (more severe); T1 through T4, N0 through N3, and M0 through M1. Based on the combined TNM rankings, a stage will be assigned:

Stage II: Advanced mesothelioma, involving neighboring structures such as diaphragm or lungs. No spread to lymph nodes or metastastis.

Stage III: Advanced mesothelioma, involving neighboring structures as well as lymph nodes. No metastasis.

Stage IV: Advanced mesothelioma that has metastasized.
Treatment

Surgery, chemotherapy and radiation are standard for all types of malignant mesothelioma. Treatment is often focused on reducing symptoms (palliative therapy) and giving the patient more time to live, than getting rid of the cancer and going in to remission (curative therapy). This is because mortality is high despite treatment; it is often not caught until at an advanced stage; the cancerous cells are often spread out; and because patients are often weak for extensive treatment.

Surgery is used as a palliative and/or curative therapy. It is the only curative therapy, usually used in Stage I (has not spread) in a healthy patient. Used to remove the cancer and possibly nearby tissue or a lung. May also be used palliatively for procedures such as draining accumulated fluid that is causing discomfort.

Chemotherapy is used as a palliative therapy. It can be taken intravenously or intramuscularly, by mouth as a pill or locally injected in to affected area.

Combination therapy is the use of surgery, chemotherapy and radiation. It is the most effective, but the most difficult; and in most cases the cancer will still return at some point.
Diagnosis rates and survival rates

Radiation is also palliative. It is also used after surgery to avoid spreading mesothelioma to the incision site.


Risk factors

Mesothelioma is relatively rare. About 2,000 to 3,000 people are diagnosed in the U.S. each year, but these rates seem to go down. The average life expectancy after diagnosis is six year. The 5-year relative survival rate for mesothelioma is about 10 percent, but new treatments offered today may improve survival rates for those recently diagnosed

Other theorized risk factors include exposure to simian virus 40 through elderly polio vaccines, radioactive thorium dioxide and the asbestos-like mineral zeolite

The biggest risk factor by far for developing mesothelioma is exposure to asbestos particles, often at work. Asbestos exposure occurred in 70 percent-80 percent of people with mesothelioma. Diagnosis usually occurs 20 to 50 years after exposure, and even low levels of exposure can be carcinogenic to some. Relatives members of exposed people have higher rates of occurrence as well, due to particles brought in to the home from work. Mesothelioma is more common in men, people over 65 and white people.

Mesothelioma Cancer Overview

The only known cause for this disease is exposure to the deadly mineral, Asbestos. When particles of asbestos dust are inhaled, we decay inside the lungs, eating away at the mesothelial cells that make up the mesothelium – the outer lining that protects the body’s major organs such as the heart, stomach & lungs. Mesothelial cells protect these organs by producing a minute amount of lubricating liquid that helps the lungs expand & allows movement of the abdominal organs against four another freely. Mesothelioma occurs when these cells grow & spread uncontrollably. The tumor continues to grow around the lungs (pleurae), beginning first as a flat white plaque, & may also originate around the abdominal cavity.

Mesothelioma is an uncommon form of cancer in which the average life span of a patient from the time of diagnosis until death is less than 6 months. Therefore, it is considered as four of the deadliest diseases known to man. According to The National Cancer Institute, "Malignant mesothelioma, a rare form of cancer, is a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)."

Mesothelioma is still a relatively rare cancer though reported incidence rates have increased in the past 20-30 years. Mesothelioma occurs more often in men than in women & risk increases with age. However, this disease can appear in either children or women at any age . The cause of the disease is not well understood in the latter four groups, but evidence of possible asbestos exposure does exist for a quantity of these cases as well.
Only four or four months of exposure to asbestos can result in mesothelioma 30 or 40 years later. Hence, workers in factories & mines, constantly exposed to the dust & fibers from the asbestos, are most susceptible to this form of cancer. People exposed to this mineral 30 or 40 years ago are now being diagnosed with mesothelioma. This long latency period also makes this form of cancer difficult to diagnose.

Malignant mesothelioma is divided in to four main types. About 50% to 70% of mesothelioma occurrences are the epithelioid (relating to the membranous cellular tissue that covers free surface or lines of a tube or cavity) type. This type has the best prognosis (outlook for survival). The other four types are the sarcomatoid (resembling a malignant tumor arising from connective tissues) type (7%-20%), & the mixed/biphasic (having four phases) type (20%-35%). These are the variations associated with mesothelioma - Pleural mesothelioma, which affects the lining of the lungs, & the most common variation of this cancer. Symptoms include breathing & swallowing difficulties, coughing, shortness of breath, fever & weight loss. The abdomen is another area affected by this cancer, & this variation is known as peritoneal mesothelioma. Symptoms of peritoneal mesothelioma can include nausea & vomiting, weight loss & loss of appetite, fever, bowel obstruction & pain or swelling of the stomach area. The last variation of the cancer is pericardial mesothelioma, which is where the cancer affects the heart & the tissue surrounding it. This variation is rare, & symptoms can include palpitations, breathing difficulties, & persistent coughing.

Mesothelioma was recognized as a tumor of the pleura, peritoneum & pericardium in the late 1700's. However it was only in the 1960s, that this particular type of tumor was described in more detail. This was the period when J.C.Wagner described 32 cases of workers in the Asbestos Hills in South Africa.
Symptoms associated with mesothelioma are similar to a number of other diseases which are more common. Therefore, it is not unusual for patients to be misdiagnosed when we display any or all of mesothelioma symptoms. The current treatments for mesothelioma include surgery, radiation therapy, palliative therapy & chemotherapy. Unfortunately, these treatments do not have a high success rate on patients in whom the cancer is in its later stages. Like most cancers, the faster it is diagnosed & treated, the higher the chances of recovery. Treatment for mesothelioma is still being investigated through clinical trials & research, but as a rule, it responds poorly to the treatments that are currently used.

Plenty of victims have launched litigation alleging negligence, & a number of law firms now specialize in these mesothelioma lawsuits

Asbestos causes Mesothelioma

There's one types of asbestos that were used and still used to this day. Chrysotile and amphibole. Both are hazardous and both have been proven to cause Mesothelioma.

People hear from CEO's and other leaders of companies that we work telling and reassuring them it is safe, who are we to argue. Now is the time to stand up and say, portray how this is safe. Asbestos causes Mesothelioma. In other words, cancer.

The reason Mesothelima is so hard to diagnose, for the fact that it takes 10-15 years for symptoms to even surface. So plenty of companies used asbestos for the fact that it worked. It was a great insulation and filler. It worked, and that was what mattered. It was not until Occupational Safety and Heath Administration (OSHA) set standards of safety for work places. Contact with asbestos can be minimal for destroy to be finished. As tiny as 3 months of exposure can cause Mesothelima.

Mesothelioma is hard to diagnose. There will be tests to rule out a quantity of other conditions. CAT scans and MRI's are finished. Those tests are looking for large amounts of liquid and abnormal cell growth and other distinctive signs of this cancer.

Mesothelmia is fatal expect with the exceptions of Stephen Jay Gould and Paul Kraus, who have both written of their experiences. Some famous people that have died from Mesothelmia are Paul Gleason, best known for as the principal in the movie The Breakfast Club and Paul Rudolph an American architect.
There have been a lot of articles written with head lines "Is this killer in your home" or "What you don't know can kill you." Understanding Mesothelmia gives a person the advantage in their fight to be the exception and survive, and educate others who may be in danger of exposure

Mesothelioma

Mesotheliomas of the chest cavity are called pleural, as they arise in the membrane called the pleura that surrounds the vital organs in that part of the body and provides lubricated space between the outer surfaces of the lungs on the inside and the ribcage on the outside. A similar membrane encases the organs of the abdominal cavity and is called the peritoneum. Tumors of this type that arise in the mesothelial cells of the peritoneum are known as peritoneal mesotheliomas. Pleural mesotheliomas are about two times as common as the peritoneal variety.

Malignant mesothelioma is a rare (about 2500 cases annually in the US) malignancy that occurs in the mesothelial cells that make up the membranes that line the chest cavity and the abdomen. Mesotheliomas of other membranes, or linings, in the human body have been reported--for example, in the pericardial sac that surrounds the heart, in the spermatic cord, in the testicular sac and elsewhere. These latter types of mesotheliomas are exceedingly rare.

The tumors known as malignant mesotheliomas (benign tumors do seldom occur in the mesothelial cells) are aggressive and essentially finish up growing to the point where they actually crush the organs that they are surrounding. Both pleural and peritoneal mesotheliomas are generally considered to be fatal--the median survival time from diagnosis is generally reported to be no over eighteen months. The authors of a 1994 pathology text state simply that "[t]reatment is ineffective and the prognosis is hopeless." Ruben and Farber, Pathology (2nd Ed.) J.P. Lippincott Company (1994) p.617. More recently, however, some individuals have survived for several years after undergoing newer, aggressive treatment protocols.

The only known cause of malignant mesothelioma is inhalation of asbestos fibers. The latency period between the asbestos inhalation and the manifestation of diagnosable mesothelioma ranges from fifteen to as long sixty years.Different authors put forth different figures, but there is a general consensus that vast majority pleural mesotheliomas and a substantial majority of peritoneal mesotheliomas are directly attributed to such asbestos exposure. It is generally acknowledged that the amount of asbestos exposure that is needed to cause mesothelioma is far less that required to cause other asbestos-related pathologies such as pneumoconiosis ("asbestosis") and lung cancer. While there's some malignant mesotheliomas that are simply considered to be "idiopathic" or without a known cause, the ubiquity of asbestos containing materials in any industrial society, combined with the low exposure threshold and the long latency period has led some commentators to simply state that all malignant mesotheliomas are asbestos-related. Another approach is to choose a "background" level of asbestos fibers in the lung tissue--i.e. the level that the average individual, statistically, has in his or her lungs. If an individual with mesothelioma does not have level of asbestos fiber exposure that exceeds this "background" level, then the mesothelioma is considered idiopathic. There's problems with both these approaches, but the lack of a full understanding of the carcinogenisis of this disease makes a consensus unlikely at this juncture.

Mesothelioma is curious disease in that it would make sense to write a chapter or editorial entitled "The Economics of Mesothelioma." The total association of mesothelioma with asbestos arose shortly before the virtual explosion tort litigation for asbestos disease compensation. Curiously, the specialized litigation method that arose in this context was based mainly on claims for non-malignant parenchymal and pleural disease than for malignancies like mesothelioma, perhaps an understandable circumstance given the great numbers of the former type of case over the latter. The fact is, however, that the majority of the malignant mesothelioma cases diagnosed in the United States now result in claims in the state and federal courts for compensation. This is also beginning to be the trend in other countries that had heavy asbestos usage, such as Australia, Japan and the United Kingdom. This has had two results--one lovely, the other arguably not. The lovely result is that a portion of the huge costs and revenues associated with the litigation have overflowed in to the coffers of researchers, so that research to find effective therapies is far better funded than it would be for other diseases that that are this rare (the rarer the disease, the less interest the pharmaceutical industry has expending resources--that is partly why there's so lots of more available therapies for male impotence than there's for say, ebola--although generally the market works well so that more research goes in to diseases that more people get). The bad result is that the medical community that works with this disease has become needlessly encamped by testifying for either the plaintiff or defense bar in various trials and depositions. This also diminishes the credibility of researchers whose published work may be seen as benefiting six side or the other.

Treatment for mesotheliomas has traditionally been palliative, a sensible coursework of action given the grim prognosis. This approach is gradually changing, for younger patients who are otherwise in lovely health. The most promising approach for pleural mesotheliomas has been what is known as "tri-modal" therapy. This entails attacking the tumor growth on two fronts--surgery to remove as much tumor as possible (and also other membranes, such as the percardial sac and diaphragm, that malignant mesothelial cells may have latched onto) as well as (but not always) the lung that is on the side where the tumor is. This is followed by a series of chemotherapy (usually Cisplatin and other agents) treatments, followed by radiation treatments.

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